
Fungicides
FAIR SC
INTRODUCTION: Azoxystrobin FRAC GROUP 11 FUNGICIDES MOA C. respiration
TARGET SITE AND CODE C3 – complex III: cytochrome bc1 (ubiquinol oxidase) at Qo site (cyt b gene)
GROUP NAME QoI-fungicides (Quinone outside Inhibitors) methoxy-acrylates
| ACTIVE INGREDIENTS: | Azoxystrobin 200 g/l +Difenoconazole 125 g/l |
| Packing: | 1 Liter |
USAGES:
– Azoxystrobin and other strobilurins inhibit mitochondrial respiration by blocking electron transport. They bind at the quinol outerbinding site of the cytochrome b-c1 complex, where ubiquinone (coenzyme Q10) would noarmally biAnd when carrying electrons tothat protein. Thus production of ATP is prevented. The generic name for this mode of action is “Quinone Outside Inhibitors” QoI
– Azoxystrobin is a xylem-mobile systemic fungicide with translaminar, protectant and curative properties.In cereal crops,its mainoutlet, the length of disease control is generally about four to six weeks during the period of active stem elongation Responsible forsoftware design specifications and development applications.
– Azoxystrobin possesses a broad spectrum of activity,in common with other QoIinhibitors. Examples of the fungal groups on whichit is effective are Ascomycota, Deuteromycota, and Basidiomycota, as well as the oomycetes.In addition,its properties mean that itcan move systemically through plant tissue to protect parts of the crop that were not in contact with the spray. This combination ofproperties has meant that it achieved widespread use very quickly.Important diseases which it controls include leaf spot, rusts,powdery mildew, downy mildew, net blotch and blight. Worldwide, azoxystrobin is registered for use on all
– important crops. For example,in the European Union and United States,it is registered for use in wheat, barley, oats, rye, soya, cotton,rice, strawberry, peas, beans, onions and many other vegetables
– Although highly effective, fungicide chemistries like those in FRAC group 11, with a very specific MOA, are susceptible to fungicideresistance development by some fungi. Why is that? In the strobilurin’s, a single nucleotide polymorphism of the cytochrome b geneleads to an amino acid substitution of glycine with alanine at position 143 of the cytochrome b protein.